GASTRIC CANCER (CANCER OF THE STOMACH)

What are the symptoms of stomach cancer?
How is cancer of the stomach diagnosed?
What treatments are available?

Gastric cancer is the third commonest cancer in men in Singapore and the second commonest cancer worldwide.
 
 
WHAT ARE THE SYMPTOMS OF STOMACH CANCER?
When the tumour is small there may be no symptoms. Patients with advanced tumors commonly present with pain in the upper abdomen. This may be accompanied by weight loss, loss of appetite, vomiting and bleeding. The latter are "alarm symptoms" and should be an indication to seek medical attention without delay.
 
 
HOW IS CANCER OF THE STOMACH DIAGNOSED?
Endoscopy is the most important and accurate investigation. This should be performed for patients with dyspepsia which persists for more than a few weeks or which does not respond to treatment, especially in people over the age of 40 years. At endoscopy the inner lining of the stomach is carefully examined and biopsies of any abnormal areas can be taken. Biopsies will prove whether cancer is present.  
Cancer of the stomach
diagnosed by endoscopy
 
 
WHAT TREATMENTS ARE AVAILABLE ?
Complete removal of the tumour by surgery is the only method of curing stomach cancer. For the majority of patients this involves removing part or all of the stomach. Surgery may also be necessary in patients with incurable cancer in order to relieve tumour complications such as obstruction or bleeding.

Chemotherapy and radiotherapy treatment given after surgery have not been very effective in preventing tumour recurrence or improving survival. Recently "neoadjuvant therapy" has been tried, which is giving chemotherapy pre-operatively to shrink the tumour and to improve resectability.